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Seth Rogen thinks his wife is "incredible" for the way she has "embraced" her mother's Alzheimer's Disease.
The 32-year-old actor and his spouse Lauren Miller helped found the organisation Hilarity For Charity (HFC), which aims to use the power of laughter to bring attention to the degenerative disease, and he admits it has forced her to share "an inherently very unhappy" part of her life.
The 'This Is The End' star said: "My wife Lauren's mom was diagnosed with early-onset Alzheimer's when she was in her early 50s. Out of a sense of desperation - and wanting to feel like we were doing something - we, along with some friends, started Hilarity for Charity, a comedy variety show.
"The fact that Lauren has embraced everything that goes along with the disease and is sharing her story? It's incredible.
"She's been forced to delve into a part of her life that is inherently very unhappy."
Seth admits Lauren sometimes finds it very difficult, but is determined to continue doing as much as possible in the hope there can one day be a cure for the degenerative condition.
He explained to People magazine: "Ultimately the hopes is to discover a cure. But in the meantime we're focusing on more tangible goals and have started a program to get scholarships for in-home care for people with Alzheimer's. I just hope we're able to capture the attention of more young people and get the disease the type of funding it deserves."

Fergie appreciates Josh Duhamel more since the birth of their son.
The Black Eyed Peas singer and her 'Transformers' actor husband welcomed son Axl into the world 13 months ago and she admits she felt "blessed" to have a spouse so knowledgeable about children because her knowledge on even basic care was limited.
The 39-year-old star said: "I'm so blessed to have the husband I have.
"He really helped me with certain things, like diaper changing and all that, because he grew up around babies and I didn't."
The 'LA Love' hitmaker, who married the 'Safe Haven' actor in 2009, admits they both have very busy schedules, but make sure to spend lots of time together at the weekend.
She told Us Weekly magazine: "Weekends are our big family days."
Fergie recently revealed Axl took his first steps in August and Josh missed the milestone.
She said: "He was at work. I felt so bad! But you know, we're both working parents so each of us are going to get different gifts."
Josh and Fergie are already hoping to expand their family again in the near future.
The blonde beauty said: "We definitely want another."

Ellen Pompeo "held hands" with her surrogate when she was inseminated.
The 'Grey's Anatomy' actress and her husband Chris Ivery recently welcomed their second daughter, Sienna, into the world via a surrogate and the couple were present for every stage of the process.
She said: "I was present for the insemination. I held her hand. So, they take the sperm...Medically, Chris has to do what he has to do and provide, and then I had to provide something as well, you know? You have to retrieve the egg.
"And then they put it together in a dish, the lab technicians, and then they make the embryo. Then they insert the embryo into the woman who will carry the child.
I was there with her when they inseminated her and we held hands. I looked into the microscope and I saw the embryo, I saw the baby, and they put it in a thingy and they inseminated her. And then we held hands and we prayed, we talked to God, and if she was meant to be. He said he was going to try to help us out and now we have a gorgeous baby girl."
The 44-year-old actress - who already has five-year-old Stella with Chris - will be "forever grateful" to the unnamed woman who agreed to carry their child.
She told talk show host Jimmy Kimmel: "This is an incredible thing to do with your life, to give the gift of carrying someone's child, so I am forever grateful and feel very blessed and grateful to her - she who will remain anonymous."

Jennifer Garner feels like she's having an affair because Ben Affleck's body has changed so much.
The 'Alexander and the Terrible Horrible No Good Very Bad Day' star is incredibly impressed with the physical transformation her spouse has undertaken while bulking up to portray Batman in 'Batman v Superman: Dawn of Justice'.
Speaking on 'Live with Kelly and Michael', she said: "You know, he has put on 30 pounds of muscle and he's 8% body fat. He looks pretty good.
"It's a little bit like, 'Whoa, who are you?' It feels like I'm having an affair. But I don't mind, I'm not complaining!"
While Jennifer is impressed with Ben's new project, he recently admitted their three kids, Violet, eight, Seraphina, five, and Samuel, two, "couldn't give a s**t" about the superhero saga because they prefer Disney's animated adventure 'Frozen'.
He said: "People always say, 'Are your kids into it?' No, they're not. If I was doing the sequel to 'Frozen', I would be a hero. My two older daughters could give a s**t about Batman.
"They love 'Frozen'. And the indignity is so great that they have now passed that affection onto my son. He's like, 'Papa, can I watch 'Frozen'?' and I'm like, 'No, dude! It's not on again!'

Emma Thompson has urged the public to follow Russell Brand's 'don't vote' campaign.
The 'Effie Gray' actress has spoken out in favour of the comedian's controversial campaign - which encouraged people to rethink their political stance by not voting in elections - and has even likened modern society to the totalitarian state featured in George Orwell's novel, '1984'.
In an interview with The Times newspaper, Emma said: "I am encouraged by people like Russell Brand saying, 'Don't vote'. I've now got to the point where I listen to reports about what's happening on the FTSE or the Dow Jones [stock exchange] and I think I'm in an Orwell [novel]."
The 55-year-old actress - who visited the Arctic with the environmental organisation Greenpeace earlier this year - also advised people to do "whatever it takes" to prevent further damage to the environment.
She told the newspaper: "I'm afraid I have just got to the stage where I can't stand it any more, what is being done in this world. I can't stand it, I can't bear the fact that they are going to drill for oil. They're not drilling for f***ing oil in the Arctic! The Arctic belongs to us, all of us, they can't be allowed to do that, so whatever it takes ... non-violent direct action, civil disobedience, you have to do it!"

Keira Knightley doesn't "condemn" cosmetic surgery.
The 'Atonement' star may think using Botox or fillers is not good for actresses because it restricts their facial movements, but she would never "condemn" anyone for having the wrinkle-smoothing treatments if it made them happier.
Talking to the Daily Mail newspaper, Keira said: "It is a drawback, not being able to move your face. But I don't think I would ever condemn any woman for doing something that made her feel better about herself.
"If she's suddenly feeling like she's the most disgusting thing in the world, and that's what she wants to do and that makes her happier then I think she should be free to do what makes her feel better in her own body, her own skin and own mind."
When the 29-year-old actress was asked if she would ever consider going under the knife, she replied: "Surgery for myself? I hope I don't. I don't plan to. but who knows?"
Keira - who stars in the new film, 'The Imitation Game' opposite Benedict Cumberbatch - explained how she had fought to keep her character Joan Clarke as unglamorous as possible because she didn't want her to be defined by her appearance.
She added: "I just wanted her not to feel like the 'girl' in the movie, and when she comes along, suddenly everyone says, 'Ah pretty!'"

Bethenny Frankel has been warned by a judge to stop wearing her daughter's clothes.
The 43-year-old reality star was criticised by a Manhattan matrimonial judge yesterday (02.10.14) for showing "poor judgement" by posting a photograph online of herself in July wearing four-year-old Bryn's Hello Kitty pyjamas and Justice Ellen Gesmer told her the decision was "ridiculous".
The judge said: "No more pyjamas!"
When Bethenny's lawyer, Allan Mayefsky, insisted the posting was just a joke, the judge replied: "It's not a joke. Her child is not a joke."
The judge - who was presiding over a hearing between Bethenny and ex-husband Jason Hoppy relating to financial information - reminded the 'Real Housewives' star the image will stay on the Internet forever and said even her own concerned friends had called her about the picture.
A trial to divide the TV star's estimated $55 million fortune is expected to take place during the coming months.
The former couple spent 16 months locked in a bitter battle over Bryn, but finally agreed to share parental duties in June.
The pair filed for divorce in December 2012 but have since been arguing over the money made during their two-year marriage after Bethenny set up her company Skinnygirl.

Charlie Sheen has branded a dental technician who accused him of making threats with a knife a "desperate troll".
The unnamed technician - who has since been dismissed from her job - told police the 'Anger Management' star had threatened his dentist while high on rock cocaine but the 49-year-old actor insists her allegations are false.
Sending a message via website TMZ, Charlie said: "Hey cholesterol pants: Maybe you should have taken the crack you so brazenly and ignorantly accused me of being on, and sold it!
"Now that you're a jobless washout and a traitor, you're gonna need the extra dough ... lick those food stamps, you desperate troll. C."
According to the website, Charlie's dentist has denied the claims of the technician, and fired her from his practice after she spoke out about his famous patient, violating privacy regulations.
A spokesperson for the former 'Two and a Half Men' star - who had sought treatment for an abscess - previously insisted any altercation was caused due to the actor experiencing a "bad reaction" to nitrous oxide.
His representative Jeff Ballard said: "Charlie went to the dentist and had a bad reaction to the nitrous oxide which the dentist administered to him. There was no knife involved and there were no illegal drugs involved as well."
The technician had claimed Charlie went "insane" and was flailing his arms when she placed a mask over his face to administer nitrous oxide, so she left the room and his bodyguard entered.
Following a "lot of commotion", Charlie's dentist - who had also been in the room along with an oral surgeon - left the room and allegedly told the technician his famous patient had gone after him with a knife, but he was unhurt.
The technician also reported to officers that Charlie's bodyguard had told the dentist the 49-year-old star was "high on rock cocaine" at the time of the altercation.

Kendra Wilkinson Baskett says her husband is having "a lot of therapy".
The 'Kendra On Top' star was left devastated when a transsexual woman claimed to have had an affair with Hank Baskett - the father of her children Hank Jr., four, and four-month-old Alijah - earlier this summer and she admits their marriage was in trouble long before the allegations were made.
Asked when their relationship started to become rocky, she said: "He was going through a lot of stuff that nobody knows about and he was trying to talk to me about it and I would not deal with it," she said, looking back on when their relationship started to become rocky.
"He was very lost. Very, very lost and I wish I would have had it in my heart to slow down a little bit and listen... right now, he's in a lot of therapy... and figuring out a way to explain everything. I don't get it."
While Hank is insistent the infidelity claims are false, Kendra admits "some of it is true" and she is still unsure about the future of their relationship.
She added: "In my eyes, life is too short and this man who I loved for six years - I believe he deserves... a second chance, if he did make a mistake.
"And right now I'm working that out. I'm working on what happened and if this was a mistake, which I believe, I'm starting to believe it was.
"If I believe that Hank had an affair on me, the divorce would have gone through already. I'm holding on to any hope I have."
And the 29-year-old beauty went on to praise the sportsman as a "perfect guy".
She told 'Access Hollywood': "At the end of the day, he comes from an amazing place and amazing background. He's a perfect guy and he's never done me wrong, he's not like some douchebag. He's not a douchebag.
"He's never treated me wrong, so if he was, I wouldn't be with him right now.
"He is an amazing father."